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Charles Hampden-Turner, who works with companies the world over on issues of culture, told me a great story about Hewlett-Packard (HP), a culture that, until its board scandal, was famous for getting its HOWs right. My friend Carl Hodges at Hewlett-Packard got a gold medal for de ance from Dave Packard, the head of the company, he told me. HP was doing R&D for the Apollo lunar landing module, and Packard wanted it out. I don t want to see it again, he told Carl. So Carl got it out of research he put it into production. And Packard was really upset with him. Later, he relented and supported the project, which allowed the descent on the moon and made a mint of money for HP. So Dave Packard gave Carl Hodges a gold medal for de ance, and he delivered it in front of everyone, so everyone knew that he was wrong and Carl was right. 12

Agras, Schneider, Arnow, Raeburn, and Telch (1989) employed the additive design in an investigation of the potential additive effects of response prevention on CBT for bulimia nervosa Participants were randomly assigned to one of four conditions: a waiting-list control group (WL); self-monitoring of caloric intake and purging behavior (SM, a condition which employed the use of nondirective techniques and thus controlled for the common factors of therapy as well as the act of monitoring one s own eating and purging behaviors); cognitive-behavioral therapy (CBT, which included selfmonitoring of eating and purging behaviors in addition to the altering of dietary habits, exposure to avoided foods, and challenging of distorted cognitions regarding diet and body image); or CBT plus response prevention of vomiting (CBT RP) The investigators concluded that after 4 months of treatment, each of the three treatment groups (ie.

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Other Types of Generators Thermal degradation of wood can also be accomplished by overheated steam; this takes place in the steam smoke generators covered by numerous patents (Fessman 1971) The sawdust is fed by a worm feeder into a reactor formed by a tilted pipe with perforated walls Overheated steam at temperatures of usually about 200 C is blown through the perforations into the sawdust- lled reactor At this considerably lower temperature, lignin does not undergo thermal degradation, and the smoke is rich in carboxylic acids and carbonyl compounds but relatively poor in phenols and polycyclic aromatic compounds In some of these generators, additional sections of the reactor serve to oxidize the volatile decomposition products by oxygenenriched air.

, SM, CBT, CBT RP) but not the WL group had shown signi cant improvement in the frequency of purging Furthermore, only the CBT group experienced signi cantly greater reduction in purging behavior as well as overall cessation of purging than did the WL group, while the SM and CBT RP groups did not differ from the WL group at treatment termination on these two main outcome measures At the 6-month follow-up assessment, only the CBT group had experienced signi cantly greater cessation of purging than did the WL group.

The process of selecting the best lot of FBS from the lots available has been described previously [Lennon et al, 1996] and will not be reviewed in detail here It should, however, be emphasized that we regard the process of serum selection as an extremely important aspect of the culture of MSCs Our experience with testing FBS dates to the time when we were working primarily with stage 24 embryonic chick limb bud mesenchymal cells We were fortunate that the lot selected for these cells also supported the proliferation of marrow-derived MSCs, although it may be argued that the ability of a single lot of serum to support both cell types is related to the concept that both sets of cells are MSCs (See Section 1) Be that as it may, we do not use stage 24 limb bud cells as part of our current assay for FBS.

From this study, we can conclude that (a) treatment gains were not due solely to the passage of time, because the WL group failed to show a signi cant reduction of symptoms at treatment termination and was signi cantly inferior to the other treatment conditions, and (b) RP did not offer therapeutic effects above and beyond the effects of CBT alone as had originally been expected In fact, it may have had a limiting effect on the improvements that clients would have experienced had they received CBT alone One important limitation in this study was that the CBT RP condition allotted less time for cognitive behavioral therapy than did the CBT condition, given that part of the session was devoted to the RP component.

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